Great Review: "...Fat redistribution and ectopic fat deposition in the liver,muscle, and heart play a major role in MetS development. There is robust body of evidence that supports that adipose tissue dysfunction impacts whole-body metabolism...."

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Great Review: “…Fat redistribution and ectopic fat deposition in the liver,muscle, and heart play a major role in MetS development. There is robust body of evidence that supports that adipose tissue dysfunction impacts whole-body metabolism….”
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That still doesn’t explain why 20 percent of the obese are metabolically normal and why 40 percent of the normal weighted are not metabolically normal or diabetic. Studies have shown that while they were normal weighted, diabetic patients were insulin resistant. Something is still missing from the equation.
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