|As the acetone to glucose pathway is not significant even when following a ketogenic diet, it is the glycerol backbone that comprises of max. 10 % of triglycerides that can be converted to glucose. However, glucose is preferentially used in glyceroneogenesis, so whenever fat is being stored, glucose is used in the process.
Regarding ketoacidosis, it doesn’t really happen in healthy or type 2 diabetic people. The reason is too high insulin and high enough availability of oxaloacetate shift the lever towards gluconeogenesis – when needed. The reason why it happens in type 1 diabetics is too low insulin and consequently too high FFA level.
|If a person was on immunosuppressant for a while that affected their liver function and when this person is off the immunosuppressant but the liver function is not back to normal then dehydration and fasting can cause their Free fatty acids to be really high causing their breath ketones and alcohol along with blood alcohol to go quite high. I have seen this case and I am trying to figure what caused the blood alcohol to go up. Looking for an explanation, if you have any idea. I know for a fact no alcohol was consumed by this person.|
|Nobody with intact adequate insulin production is going to go into ketoacidosis, period, no matter what diet they are eating.
At the same time, everyone with inadequate insulin production is going to go into ketoacidosis, no matter what diet they are eating.
Ketoacidosis is just plain and simple insulin inadequacy.